Tel: +381 (0)21 452-910, +381 (0)21 420-758. Part of Colgate Sensitive Pro-Relief (Toothpaste): 1.9 out of 5 stars from 91 genuine reviews on Australia's largest opinion site ProductReview.com.au. The datasets analysed during the current study are available from the corresponding author on reasonable request. SCASS and VAS were introduced on each visit as primary and secondary outcome measures, respectively. When it begins to interfere with oral hygiene, it can also lead to poor oral health outcomes. [33] again reported a 54% clinical reduction in DH with Pro-argin in eight weeks clinical trial using SCASS. All the treatment groups subjected to testing in the present study revealed a considerable clinically significant symptomatic reduction in DH relative to the pre-treatment condition that was also statistically significant. 2008;29(8):1S-35S. HOW LONG CAN A PATIENT USE Colgate SENSITIVE INSTANT Relief Repair & Prevent? Clinical efficacy of BioMin F, Colgate sensitive pro-relief and Sensodyne rapid action dentifrices in DH [Internet]. 2. Dentin hypersensitivity (DH) is a sharp toothache that influences a patients' oral health-related quality of life. Statistical Package for the Social Sciences software v.21.0. However, there is a substantial possibility that these fluoridated dentifrices can reduce DH. Dentifrices-containing Pro-argin showed a significant reduction in DH with mean scores of (3.052.17) followed by strontium acetate (3.751.97) followed by FCPS (5.301.83) one minute after application. The secondary objective of the study was to compare the clinical efficacy of Pro-argin, strontium acetate, and FCPS for immediate and sustained treatment response in DH that was measured on SCASS as a primary outcome measure and VAS as secondary outcome measure at efficacy intervals of one minute, day-three, week two, four and six. Patel VR, Shettar L, Thakur S, Gillam D, Kamala DN. A total of 128 participants completed the trial. All rights reserved. 2017;71:18. Colgate SENSITIVE INSTANT Relief Repair & Prevent Toothpaste is an everyday toothpaste. was used for statistical analysis. Further, it leaves a durable, mineral-enriched layer on the exposed dentin to help protect against future dentin hypersensitivity. With its unique Pro-Argin technology, this sensitive toothpaste will give you instant* relief from sensitivity as it helps to seal and repair the sensitive areas of your teeth**. Colgate Sensitive Pro-relief Instant Relief. Pro-Argin Technology with arginine and an insoluble calcium compound, zinc and 1450ppm fluoride. Hu et al. Dentin hypersensitivity is characterized by a short, sharp pain arising from open dentin tubules in exposed dentin in response to external stimuli, which cannot be attributed to any other defect or disease. Panagakos F, Schiff T, Guignon A. Dentin hypersensitivity: effective treatment with an in-office desensitizing paste containing 8% arginine and calcium carbonate. It remains a prevalent global disease with two different treatment modalities of home-care desensitisation with the over-the-counter (OTC) desensitisers such as potassium, 2012;12(3):2208. Colgate Sensitive Pro Relief Whitening Toothpaste 75ml tube (Pack of 4) Instant and Lasting Relief Clinically Proven with Active Ingredients We have a surprise for you Find out all personalised promo codes that you are eligible for. 2009;22:3A-7A. Dentin hypersensitivity treatments work in one of two ways. Moreover, the occluding potential of Pro-argin has also been ascertained in a previous in vitro analysis conducted by Lavender et al. Poster #0742, March 2018 AADR. [16] in a systematic review in 2015. It revealed an immediate improvement with strontium acetate more than Pro-argin on SCASS. A meta-analysis by Grnberg et al. (Table 1) (Fig. Benefits: Colgate Sensitive Prevent and Repair is clinically proven to provide superior relief vs Sensodyne Extra Whitening at 8 weeks1 Long-lasting relief from hypersensitivity with continued use Superior sensitivity relief at 8 weeks vs the leading Sensodyne toothpaste variant 1 Helps protect teeth against cavities and promotes healthy gums (with regular brushing). Product Details Page . volume21, Articlenumber:498 (2021) 2017;457:2530. The permanent management of DH is being investigated with the remineralisation potential of bioactive agents in dentinal tubules. Product Details For instant relief, apply directly to the sensitive tooth with finger tip, and massage gently for 1 minute, once a week or less frequently. J Clin Exp Dent. (US). We discuss how this innovative technology works to provide patients with rapid and long-lasting relief from dentin hypersensitivity. Innehller slipmedel med ltt polerande effekt p flckar samt fluor som minskar risken fr karies. Difference in effectiveness between strontium acetate and arginine-based toothpastes to relieve dentin hypersensitivity. 2009;20(1):106. 2017;30(4):2216. WHAT IS THE FLUORIDE CONTENT OF Colgate SENSITIVE INSTANT Relief Repair & Prevent TOOTHPASTE? See patient relevant information on Colgate.com. 2009; 20 (Spec Iss): 1722. * with direct application and daily brushing Benefits Exclusive Pro-Argin formula Prevents sensitivty coming back Dentifrices were removed carefully after one minute of undisturbed application by rinsing the air lightly with an air syringe, and the subject was asked to spit. Table 3 demonstrates the percent change in the mean scores of DH on SCASS relative to baseline within the group for each treatment arm. Table 2 presents descriptive statistics of the primary analysis population as the primary statistical analysis was performed for 47 males and 81 females of age ranging from 18 to 50years with a mean age of 34.18.9. Participants were asked to pick up the envelope from the box. Internal report 2018, 5. Shiau HJ. The widely accepted hydrodynamic theory proposes that stimuli can alter the behavior of fluid in the dentin tubules, activating intra-dental nerve fibers and causing pain. 2016;8:114. Significantly greater sensitivity reduction with twice - daily brushing compared to control toothpaste with potassium ions. Naturally, the researchers wondered whether it could help shield a person from acquiring the virus. Identifier NCT 04249336. 2020;99(5):51422. * For instant relief, apply directly to the sensitive tooth with finger tip and gently massage for 1 minute. For instant relief, apply directly to each sensitive tooth surface and massage for one minute, up to twice a day. Published literature [16, 31, 43] has determined that all previous trials on treating DH were conducted on smaller samples, which might have prevented the results from being extrapolated on the general population. In addition, patients were educated regarding the cause of the disease for prevention and awareness of oral hygiene measures, brushing techniques, and dietary influences in DH. However, the manufacturers of the tested dentifrices were acknowledged in the study [34], so information bias wasexpected in the conducted trial. The study's primary objective was to investigate pain relief in one minute with Pro-argin and strontium acetate in DH measured on SCASS as a primary outcome measure and VAS as a secondary outcome measure. it is in a rubbish bin now. Effect of dentin hypersensitivity treatment on oral health related quality of lifea systematic review and meta-analysis. IRB-1351/DUHS/Approval/2019/184. More robust trials with a large number of participants are recommended for furtherassessing the impact of DH on the oral health-related quality of life and the difference in the effectiveness of treatments. For lasting relief and gum protection, apply twice daily using a sensitive toothbrush, making sure to brush all surfaces of teeth including sensitive areas. Then, the repeated measure was obtained after five minutes for previous pain recovery, and dentifrices were provided to the patient for self-application. The first post-treatment measure of SCASS and VAS scores was obtained immediately after removing dentifrices from teeth. The burden of dentine hypersensitivity. Compared to stannous fluoride/sodium fluoride and novamin/sodium fluoride. The primary analysis population could be described as 32 participants per treatment group after lost to follow-ups of 12 out of 35 enrolled in the six-week trial who responded to the air blast stimulus for the primary outcome measure of treatment response one minute after topical application and after three days and two, four and six weeks subsequently, on SCASS with scores of2. OTC dentifrices were applied and massaged gently with the applicator on at least two sensitive teeth per subject at two different sites, including cementoenamel junction and exposed dentinal surface, by the doctor in the office during the first visit. They explored greater tubular occlusion potential and more acid resistance of Pro-argin in comparison to FCPS after subsequent seven days of application on dentinal discs [38]. SHOULD A PATIENT CONTINUE USING Colgate SENSITIVE INSTANT Relief Repair & Prevent TOOTHPASTE ONCE THE DENTINE SENSITIVITY HAS GONE? Blocks the pain of sensitive teeth. Manage cookies/Do not sell my data we use in the preference centre. Terms and Conditions, Ingredients *Potassium Nitrate I want to acknowledge the administrative faculty and staff assistants in the Department of Periodontology for facilitation in data collection. The probable reason for variations between this clinical trial and previously conducted studies could be attributed to racial or ethnic differences between the conducted trials. Colgate Sensitive Instant Relief Repair & Prevent Toothpaste starts blocking sensitivity pain instantly*. observed a significantly greater reduction in sensitivity from air and tactile stimuli when compared to a potassium ion toothpaste, an effect sustained at two, four and eight weeks of use. Comparative evaluation of the efficacy of three commercially available toothpastes on dentin hypersensitivity reduction: an 8-week clinical study. Vu Pham T, Anh Nguyen T. Clinical evaluation of the desensitizing efficacy of a paste containing 8% arginine and calcium carbonate. Zinc helps strengthen gums and prevent gum recession a key cause of sensitivity1,2,3. Bakri MM, Hossain MZ, Razak FA, Saqina ZH, Misroni AA, Ab-Murat N, et al. Colgate Sensitive Instant* Relief Enamel Repair Toothpaste gives you clinically proven lasting relief** from sensitivity for 8 weeks when you use it twice a day. If the enamel is too thin, has tiny tubules that reveal the underlying dentin, or is worn down in some places. Explore the videos and articles found on this page to assist in better oral care. With regular use, it reduces teeth sensitivity and helps to strengthen gums and prevent gum recession. For instant relief, just apply directly to the sensitive tooth with fingertip and gently massage for one minute. BMC Oral Health 21, 498 (2021). Poster #3406, July 2018 IADR. The Colgate Sensitive Pro Relief range features toothpastes that provide relief for sensitive teeth while addressing other common oral health concerns: Colgate Sensitive Pro Relief Repair and Prevent to protect against gingival recession. 2009;20 (Spec Iss):123130. Moreover, FCPS as a new bioactive material revealed promising potency of sustainable management of DH in a previously conducted trial by Ashwini et al. 6 Ipsos, Romania Patient Experience Programme on Colgate SENSITIVE PRO-Relief, results collected after 2-week trial, 545 respondents, 2015. The maximum sampling time was 15min. It contains clinically proven Pro-Argin technology which provides instant and lasting sensitivity relief. Made by one of the best-known oral care companies in Australia, it has been clinically proven to provide both instantaneous and lasting relief from sensitivity, whilst also: Fighting cavities. Another study by Vu Pham and Anh Nguyen reported clinical improvement in DH by 38.9% on SCASS and 40.2% on VAS for mechanical stimulated DH immediately after application of Pro-argin [25]. Frequency of dentin hypersensitivity: a cross-sectional study. PubMedGoogle Scholar. Venkataramana S, Jeyaraman SK, Kothimbakkam SSK, Chellathurai BNK. Product Benefits. Many patients tolerate the pain of sensitive teeth because theyre unaware of simple but highly effective answers like Pro-Argin technology. In addition, they were responding to air-blast stimulus on the Schiff cold air sensitivity scale (SCASS) with scores2 [22]. However, Pro-argin showed more clinical improvement in air blast and mechanically stimulated DH compared to 8% strontium acetate, as shown in Tables 4 and 5. . 2016;27(4):916. Gently removes stains and helps restore the natural whiteness of your teeth. To alleviate their tooth sensitivity problem, by using Colgate Sensitive Pro-Relief will give them lasting relief and they can drink ice water freely. For instant relief, just apply directly to the sensitive tooth with finger tip and gently massage for one minute. Am J Dent. Therefore, this trial was planned to investigate the clinical efficacy of Pro-argin and strontium acetate for immediate pain relief in DH after one minute of topical application to fill the research gap associated with limited published evidence and risk of bias in selection, performance, attrition, and reporting as predicted by Pessoa et al. It was measured by assaying change in SCASS scores of pains with Pro-argin and 8% strontium acetate after one minute of topical application on the sensitive teeth. J Clin Dent 20 (2009), special issue 17-22, 3. Dentin hypersensitivity. Colgate Sensitive Instant Relief Enamel Toothpaste with Pro-Argin technology to help seal and repair the sensitive areas of teeth. J Clin Dent. 2013;41:S317. Colgate Sensitive Pro-Relief Instant Relief works as a shield that blocks pathways to pain instantly. 0. This trial was registered in an ICMJE approved registry at https://clinicaltrials.gov/) under protocol Identifier: NCT04249336 [19] following the CONSORT guidelines [20] for parallel-group randomized trials after approval from the Institutional Review Board of Dow University of Health Sciences with reference no. Directions for Use: For instant relief, apply directly to the sensitive tooth with finger tip and massage gently for 1 minute, up to twice a day and for children 6-12 years once a week or less frequently. Clin Cosmet Investig Dent. 1). Width 17 Height 5 Depth 3.8 Show More Payment & Refunds Size: 75ml (Approx.) The Gum Health Physical is a new interactive digital tool you can use to quickly evaluate your patients in-office, and give them a personalized report they can use at home. Colgate Total with stannous fluoride also offers more benefits than ever before, including sensitivity relief, improved enamel strength* and odor neutralization* (*based on in vitro studies).Colgate Total Advanced Whitening is a tooth whitening toothpaste that provides stain removal and prevention. The prevalence of DH was found to vary from about 5 to 62% owing to the use of different diagnostic and measuring tools and age groups in the published literature, with the best average estimate of 34% worldwide [3]. The impact of FCPS, Pro-argin, and strontium acetate-based treatments of DH on the oral health-related quality of life together with the difference in the effectiveness of treatments were assessed individually rather than in groups in the current six-week trial. How to use Colgate Toothpaste relieves the discomfort of tooth irritation by still addressing the root causes. Plugging the channels that lead to sensitive tooth nerves to help relieve sensitivity. J Clin Dent. Participants analyzed per group were more than thirty fulfilling the requirement of Holland's guidelines for conducting clinical trials for the management of DH [42]. Compend Contin Educ Dent. However, they also suggested further comparative evaluations of two dentifrices with large sample sizes as limited scientific evidence was found in previous studies [16]. All the treatment groups showed statistically significant improvement in DH with p<0.001 relative to baseline at all time points. Great Savings & Free Delivery / Collection on many items. Toothpaste doesn't only clean your teeth; we have products to help with a variety of tooth issues like sensitivity and more. Our study included an Asian population, and most of the published literature was associated with the Caucasian population. Shrimathi S. Effect of BiominF, NovaminR, Argin and nanohydroxy particles containing dentifrices on dentine hypersensitivity and gingivitis among 3544 years aged population of Madurai district: a randomized controlled trial (RCT). Book Grading of Recommendations, Assessment, Development and Evaluations. Schulz KF, Altman DG, Moher D. CONSORT 2010 Statement: updated guidelines for reporting parallel group randomised trials. Colgate SENSITIVE INSTANT Relief Repair & Prevent Toothpaste with Pro-Argin Technology and Zinc. It has stannous fluoride as an active ingredient. J Oral Rehabil. Colgate Sensitive Pro Relief was compared to a leading brand of desensitizing toothpaste containing stannous fluoride in a laboratory study, with confocal laser scanning microscopy and a novel imaging program used to qualify dentinal tubule occlusion. However, we can conclude that both Pro-argin and strontium acetate-based dentifrices disrupt the pathophysiology of DH and are effective for immediate pain relief even one minute after application on sensitive teeth. 3. The sealed envelope contained details of unique subject numbers assigned individually in ascending order, group titles, and treatment codes and was placed in the box. Helps repair teeth by forming a mineral layer that re-constructs the sensitive part of the tooth, with regular use; Seals the open nerve channels for instant relief, and helps prevent sensitivity from re-occurring; Plus the freshness you trust from Colgate who examined FCPS and Pro-argin formulations in 2018. 4Intervention D denotes Colgate Total. [41] was performed in 2017 and reported inappropriate statistical methodologies related to the normal distribution of data and equality of variances, along with lacking information in 77.1% of the thirty-five randomised trials on DH management. J Clin Dent 2009; 20 (Spec Iss): 123-130. 2020;99(5):51422. This site is intended for healthcare professionals only. Dentifrices-containing Pro-argin showed a significant reduction in DH with mean scores of (4.201.70) followed by strontium acetate (4.651.87) followed by FCPS (5.101.88) one minute after application. compared Colgate Sensitive Pro Relief to another leading brand that desensitizes with a 2% potassium ion formula. Can be used after the Colgate Sensitive Pro-Relief Desensitizing Paste. Colgate Sensitive Pro-Relief Instant Relief Sensitive Toothpaste - 75ml More Images Colgate Sensitive Pro-Relief Instant Relief works as a shield that blocks pathways to pain instantly. 2019;81:16. 2010;11:32. Register now and gain access to: 8 hours ECPD Product samples Patient materials Register here * For instant relief, apply directly to the sensitive tooth with finger tip and gently massage for 1 minute. In addition, they should be reproducible and clinically relevant to stimuli triggering pain in DH [35]. 75 ml. Prevalence of dentin hypersensitivity: systematic review and meta-analysis. Colgate SENSITIVE INSTANT Relief Repair & Prevent Toothpaste contains Sodium Fluoride (1450ppmF) the recommended fluoride level for effective caries prevention.4. The findings have revealed that both statistically and clinically significant change in mean scores of DH was observed with Pro-argin and 8% strontium acetate with p<0.05 relative to baseline for immediate and sustained relief from DH using clinical parameters of SCASS and VAS. The study's primary objective was to investigate pain relief in one minute after topical application of Pro-argin and strontium acetate on sensitive teeth in DH. CONSORT flow chart. Baseline scores were recorded to measure the intensity of pain due to DH on SCASS with scores2 [22] against air blast stimulus with a triple syringe of the dental unit and on a linear VAS of 10cm length with scores4cm [23], against mechanical stimulus with a dental probe and water jet stimulus with a triple syringe. J Clin Dent. 2017;2017:2. The next study outcome of our study wasrelated to 8% strontium acetate with clinical reduction of 37.6% on SCASS and 46% on VAS from baseline using mechanical and water jet stimuli immediately after topical application on sensitive teeth as depicted in Tables 3, 5, and 6.
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